Educational and harm-reduction focused

Explore psychoactive compounds like never before.

Why can some molecules reshape the mind and perception? PsycheDB is a place to learn how and why these compounds act on the body and brain. It brings together chemical data, binding affinities, pharmacokinetics and toxicology, all carefully sourced, and sets out to visualize the complex network that connects them. Above all, it is a place to stay curious and to look deeper into this field of research.

Psychedelics Dissociatives Entactogens 5-HT2A DAT MOR
131 Substance profiles
76 Biological targets
778 Cited measurements
100% Sourced

Scientific knowledge comes first. PsycheDB documents these compounds to build understanding, not to promote their use. Avoiding non-medical substance use avoids its associated risks. Do not stop prescribed treatment without medical advice. If you or someone else does, it is worth knowing the risks beforehand, from drug checking and dosing to dangerous combinations and what to do in an emergency. Beyond the physical risks, the legal status of these substances varies widely from country to country, and possession alone can carry serious consequences depending on where you are.

Read the harm reduction guide →
What every entry gives you

Anatomy of a profile

Here is what a profile looks like, using LSD as an example. Every entry follows the same shape, moving from identity and chemistry through pharmacology to safety, and sources and evidence gaps are shown within each profile.

LSD structure

LSD

C₂₀H₂₅N₃O · 323.4 g/mol
Psychedelic · Ergoline Serotonergic agonist
Selected receptor measurements
5-HT2A EC₅₀ 1.52 nM
5-HT2B EC₅₀ 15.3 nM
5-HT2C EC₅₀ 35.1 nM
ClassErgoline psychedelic
Common routesOral, sublingual
Onset20 to 60 min
Duration8 to 12 h
1
Overview & identity

A plain-language overview and the full chemical identity, including CAS, PubChem CID, InChIKey, SMILES, chemical class and known synonyms.

2
Effects & dosing

Commonly reported subjective effects alongside reference dose ranges and durations by route, each framed with harm-reduction context.

3
Chemistry & physical properties

Molecular formula and molar mass, plus experimental or predicted properties, labelled where available, such as melting and boiling point, density, pKa, LogP and solubility.

4
Pharmacodynamics

The mechanism of action, the biological targets involved, and a receptor fingerprint with binding and functional measurements shown separately, including species and assay context.

5
Pharmacokinetics

How the body handles it, from bioavailability and time to peak through half-life, volume of distribution, protein binding, metabolism and excretion.

6
Safety, legal status & sources

Toxicology and interactions, controlled-substance status by country, and a numbered bibliography listing every source the entry draws on.

Two compounds, side by side. Compare receptor measurements and fingerprints in one view.

Open the comparison tool →

Start from a target

These are the targets the most substances in the library act on. Pick one to explore the library's recorded measurements, with binding and functional results shown separately.